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FCRL3 抗体 (AA 122-222) (HRP)

This anti-FCRL3 antibody is a 兔 多克隆 antibody detecting FCRL3 in ELISA. Suitable for 人.
产品编号 ABIN7152661
发货至: 中国

Quick Overview for FCRL3 抗体 (AA 122-222) (HRP) (ABIN7152661)

抗原

See all FCRL3 抗体
FCRL3 (Fc Receptor-Like 3 (FCRL3))

适用

  • 13
  • 2
  • 2

宿主

  • 9
  • 4

克隆类型

  • 9
  • 4
多克隆

标记

  • 10
  • 1
  • 1
  • 1
This FCRL3 antibody is conjugated to HRP

应用范围

  • 6
  • 5
  • 4
  • 4
  • 2
ELISA
  • 抗原表位

    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 122-222

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Fc receptor-like protein 3 protein (122-222AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    FCRL3 (Fc Receptor-Like 3 (FCRL3))

    别名

    FCRL3

    背景

    Background: Promotes TLR9-induced B-cell proliferation, activation and survival but inhibits antibody production and suppresses plasma cell differentiation. Enhances activation of NF-kappa-B and MAPK signaling pathways in TLR9 stimulated B-cells (PubMed:23857366). Has inhibitory potentional on B-cell receptor (BCR)-mediated signaling, possibly through association with SH2 domain-containing phosphatases. Inhibits cell tyrosine phosphorylation, calcium mobilization and activation-induced cell death induced through BCR signaling (PubMed:19843936). Regulatory T-cells expressing FCRL3 exhibit a memory phenotype, are relatively nonresponsive to antigenic stimulation in presence of IL2 and have reduced capacity to suppress the proliferation of effector T-cells (PubMed:20190142, PubMed:19494275).

    Aliases: CD307c antibody, Fc receptor homolog 3 antibody, Fc receptor-like protein 3 antibody, FcR-like protein 3 antibody, FcRH3 antibody, FcRL3 antibody, FCRL3_HUMAN antibody, hIFGP3 antibody, IFGP family protein 3 antibody, IFGP3 antibody, Immune receptor translocation-associated protein 3 antibody, Immunoglobulin superfamily receptor translocation associated protein 3 antibody, IRTA3 antibody, SH2 domain-containing phosphatase anchor protein 2 antibody, SPAP2 antibody

    UniProt

    Q96P31
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