FAIM3 抗体 (AA 18-251)
Quick Overview for FAIM3 抗体 (AA 18-251) (ABIN7152579)
抗原
See all FAIM3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 18-251
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Fas apoptotic inhibitory molecule 3 protein (18-251AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))
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别名
- FCMR
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背景
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Background: May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
Aliases: Faim3 antibody, FAIM3_HUMAN antibody, Fas apoptotic inhibitory molecule 3 antibody, Fc fragment of IgM receptor antibody, Fc mu receptor antibody, FCMR antibody, IgM Fc receptor antibody, Immunoglobulin mu Fc receptor antibody, Regulator of Fas induced apoptosis antibody, Regulator of Fas-induced apoptosis Toso antibody, TOSO antibody
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UniProt
- O60667
抗原
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