FBXO9 抗体 (AA 13-111) (FITC)
Quick Overview for FBXO9 抗体 (AA 13-111) (FITC) (ABIN7152453)
抗原
See all FBXO9 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 13-111
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human F-box only protein 9 protein (13-111AA)
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亚型
- IgG
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anti-F-Box Protein 9 (FBXO9) (AA 13-111) antibody
FBXO9 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 9 (FBXO9) (AA 338-447) antibodyFBXO9 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G12 unconjugated
anti-F-Box Protein 9 (FBXO9) (AA 1-437) antibodyFBXO9 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-F-Box Protein 9 (FBXO9) (Middle Region) antibodyFBXO9 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 马, Pig, 兔, 豚鼠, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 9 (FBXO9) antibodyFBXO9 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 9 (FBXO9) (AA 179-228) antibodyFBXO9 适用: 人, 小鼠, 大鼠, Cow, 犬, 小鸡, 马, Pig, 兔, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 9 (FBXO9) (AA 346-373), (C-Term) antibodyFBXO9 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- FBXO9 (F-Box Protein 9 (FBXO9))
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别名
- FBXO9
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背景
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Background: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of TTI1 and TELO2 in a CK2-dependent manner, thereby directly regulating mTOR signaling. SCF(FBXO9) recognizes and binds mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, the SCF(FBXO9) does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is activated due to the relief of feedback inhibition by mTORC1.
Aliases: Cross-immune reaction antigen 1 antibody, dJ341E18.2 antibody, DKFZp434C0118 antibody, F-box only protein 9 antibody, Fbp24 antibody, FBX09 antibody, FBX9 antibody, FBX9_HUMAN antibody, Fbxo9 antibody, KIAA0936 antibody, NY REN 57 antibody, OTTHUMP00000016628 antibody, OTTHUMP00000016629 antibody, OTTHUMP00000214588 antibody, Renal carcinoma antigen NY-REN-57 antibody, VCIA1 antibody
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UniProt
- Q9UK97
抗原
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