FBXO7 抗体 (AA 353-522)
Quick Overview for FBXO7 抗体 (AA 353-522) (ABIN7152450)
抗原
See all FBXO7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 353-522
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交叉反应
- 人, 小鼠
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human F-box only protein 7 protein (353-522AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- FBXO7 (F-Box Protein 7 (FBXO7))
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别名
- FBXO7
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背景
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Background: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy (mitophagy) by targeting PARK2 to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination.
Aliases: F box only protein 7 antibody, F box protein 7 antibody, F-box only protein 7 antibody, FBX antibody, FBX07 antibody, FBX7 antibody, FBX7_HUMAN antibody, Fbxo7 antibody, PARK15 antibody, PKPS antibody
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UniProt
- Q9Y3I1
抗原
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