F-Box Protein 3 抗体 (AA 276-376) (FITC)
Quick Overview for F-Box Protein 3 抗体 (AA 276-376) (FITC) (ABIN7152427)
抗原
See all F-Box Protein 3 (FBXO3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 276-376
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human F-box only protein 3 protein (276-376AA)
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亚型
- IgG
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- F-Box Protein 3 (FBXO3)
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别名
- FBXO3
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背景
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Background: Substrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.
Aliases: F Box G - Domain 3 antibody, F box only protein 3 antibody, F box protein 3 antibody, F box protein FBX3 antibody, F-box only protein 3 antibody, FBA antibody, FBX3 antibody, FBX3_HUMAN antibody, FBXO3 antibody
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UniProt
- Q9UK99
抗原
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