EYA2 抗体 (AA 1-514)
Quick Overview for EYA2 抗体 (AA 1-514) (ABIN7152359)
抗原
See all EYA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-514
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Eyes absent homolog 2 protein (1-514AA)
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亚型
- IgG
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anti-Eyes Absent Homolog 2 (Drosophila) (EYA2) (AA 164-271) antibody
EYA2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2F8 unconjugated
anti-Eyes Absent Homolog 2 (Drosophila) (EYA2) (AA 1-538) antibodyEYA2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Eyes Absent Homolog 2 (Drosophila) (EYA2) (Internal Region) antibodyEYA2 适用: 人, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Eyes Absent Homolog 2 (Drosophila) (EYA2) (AA 200-249) antibodyEYA2 适用: 人, 大鼠, 马, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Eyes Absent Homolog 2 (Drosophila) (EYA2) (AA 300-400) antibodyEYA2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Eyes Absent Homolog 2 (Drosophila) (EYA2) (AA 216-244) antibodyEYA2 适用: 人 WB 宿主: 兔 Polyclonal RB37025 unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))
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别名
- EYA2
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背景
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Background: Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5. Tyrosine phosphatase that dephosphorylates \'Tyr-142\' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. \'Tyr-142\' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis. Plays an important role in hypaxial muscle development together with SIX1 and DACH2, in this it is functionally redundant with EYA1.
Aliases: EAB 1 antibody, EAB1 antibody, EYA 2 antibody, EYA transcriptional coactivator and phosphatase 2 antibody, EYA2 antibody, EYA2_HUMAN antibody, eyes absent 2 homolog (Drosophila) antibody, Eyes absent homolog 2 (Drosophila) antibody, Eyes absent homolog 2 antibody, Translation of this uORF probably lowers the translation efficiency of EYA2 antibody
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UniProt
- O00167
抗原
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