SERF2 抗体 (AA 107-224) (Biotin)
Quick Overview for SERF2 抗体 (AA 107-224) (Biotin) (ABIN7152339)
抗原
See all SERF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 107-224
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Extracellular serine/threonine protein kinase FAM20C protein (107-224AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SERF2 (Small EDRK-Rich Factor 2 (SERF2))
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别名
- FAM2C
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背景
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Background: Golgi serine/threonine protein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs and plays a key role in biomineralization of bones and teeth (PubMed:22582013, PubMed:23754375, PubMed:25789606). Constitutes the main protein kinase for extracellular proteins, generating the majority of the extracellular phosphoproteome (PubMed:26091039). Mainly phosphorylates proteins within the Ser-x-Glu/pSer motif, but also displays a broader substrate specificity (PubMed:26091039). Phosphorylates casein as well as a number of proteins involved in biomineralization such as AMELX, AMTN, ENAM and SPP1 (PubMed:22582013, PubMed:25789606). In addition to its role in biomineralization, also plays a role in lipid homeostasis, wound healing and cell migration and adhesion (PubMed:26091039).
Aliases: C76981 antibody, Dentin matrix protein 4 antibody, DKFZp547C074 antibody, DMP-4 antibody, DMP4 antibody, DMP4_HUMAN antibody, Extracellular serine/threonine protein kinase Fam20C antibody, Fam20c antibody, Family with sequence similarity 20 member C antibody, GEF CK antibody, Golgi enriched fraction casein kinase antibody, Protein FAM20C antibody, RNS antibody
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UniProt
- Q8IXL6
抗原
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