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- 抗原 See all EXOSC3 抗体
- EXOSC3 (Exosome Component 3 (EXOSC3))
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抗原表位
- AA 2-275
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EXOSC3 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Exosome complex component RRP40 protein (2-275AA)
- 亚型
- IgG
- Top Product
- Discover our top product EXOSC3 Primary Antibody
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anti-Exosome Component 3 (EXOSC3) (AA 1-275) antibody
EXOSC3 适用: 人 WB, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 5C3 unconjugated
anti-Exosome Component 3 (EXOSC3) (AA 1-275) antibodyEXOSC3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 3 (EXOSC3) (AA 1-275) antibodyEXOSC3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Exosome Component 3 (EXOSC3) (AA 176-274) antibodyEXOSC3 适用: 人 ELISA, IP 宿主: 小鼠 Monoclonal 3E5 unconjugated
anti-Exosome Component 3 (EXOSC3) (C-Term) antibodyEXOSC3 适用: 人, 小鼠, 犬, 兔, Cow, 豚鼠, 马, Pig, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 3 (EXOSC3) (AA 81-130) antibodyEXOSC3 适用: 人, 小鼠, 犬, 兔, Cow, 豚鼠, 马, Pig, 猴, 小鸡, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 3 (EXOSC3) antibodyEXOSC3 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 1D6 unconjugated
anti-Exosome Component 3 (EXOSC3) (C-Term) antibodyEXOSC3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 3 (EXOSC3) (C-Term) antibodyEXOSC3 适用: 人, 小鼠, 犬, 兔, Cow, 豚鼠, 马, Pig, 斑马鱼, 猴, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 3 (EXOSC3) antibodyEXOSC3 适用: 人 WB 宿主: 小鼠 Monoclonal 4C9 unconjugated
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- EXOSC3 (Exosome Component 3 (EXOSC3))
- 别名
- EXOSC3 (EXOSC3 产品)
- 别名
- PCH1B antibody, RP11-3J10.8 antibody, RRP40 antibody, Rrp40p antibody, bA3J10.7 antibody, hRrp-40 antibody, p10 antibody, 2310005D06Rik antibody, AI593501 antibody, Rrp40 antibody, im:7140537 antibody, zgc:112345 antibody, exosome component 3 antibody, exosome component 3 L homeolog antibody, EXOSC3 antibody, exosc3.L antibody, Exosc3 antibody, exosc3 antibody
- 背景
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Background: Non-catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC3 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits through contacts with EXOSC9 and EXOSC5.
Aliases: EXOSC3 antibody, RRP40 antibody, CGI-102Exosome complex component RRP40 antibody, Exosome component 3 antibody, Ribosomal RNA-processing protein 40 antibody, p10 antibody
- UniProt
- Q9NQT5
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome
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