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EIF3E 抗体 (AA 1-445)

The 兔 多克隆 anti-EIF3E antibody is suitable to detect EIF3E in samples from 人. It has been validated for ELISA 和 IHC.
产品编号 ABIN7152153
发货至: 中国
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Quick Overview for EIF3E 抗体 (AA 1-445) (ABIN7152153)

抗原

See all EIF3E 抗体
EIF3E (Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))

适用

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宿主

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克隆类型

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多克隆

标记

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This EIF3E antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 1-445

    原理

    EIF3E Antibody

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Eukaryotic translation initiation factor 3 subunit E protein (1-445AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    EIF3E (Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))

    别名

    EIF3E

    背景

    Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Required for nonsense-mediated mRNA decay (NMD), may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.

    Aliases: eIF-3 p48 antibody, eIF3e antibody, EIF3E_HUMAN antibody, EIF3S6 antibody, eIFe antibody, Eukaryotic translation initiation factor 3 subunit 6 antibody, Eukaryotic translation initiation factor 3 subunit E antibody, eukaryotic translation initiation factor 3, subunit 6 (48kD) antibody, INT6 antibody, mammary tumor-associated protein INT6 antibody, murine mammary tumor integration site 6 (oncogene homolog) antibody, Viral integration site protein INT-6 homolog antibody

    UniProt

    P60228

    途径

    Ribonucleoprotein Complex Subunit Organization, Hepatitis C
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