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EIF3A 抗体 (AA 1288-1379)

This 兔 多克隆 anti-EIF3A antibody specifically detects EIF3A in WB, ELISA 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN7152145
发货至: 中国
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Quick Overview for EIF3A 抗体 (AA 1288-1379) (ABIN7152145)

抗原

See all EIF3A 抗体
EIF3A (Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A))

适用

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宿主

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克隆类型

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多克隆

标记

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This EIF3A antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 1288-1379

    原理

    EIF3A Antibody

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Eukaryotic translation initiation factor 3 subunit A protein (1288-1379AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    EIF3A (Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A))

    别名

    EIF3A

    背景

    Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Essential for the initiation of translation on type-1 viral ribosomal entry sites (IRESs), like for HCV, PV, EV71 or BEV translation (PubMed:23766293, PubMed:24357634). In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2 (PubMed:18056426).

    Aliases: centrosomin homolog antibody, cytoplasmic protein p167 antibody, eIF 3 theta antibody, eIF-3-theta antibody, EIF3 antibody, eIF3 p167 antibody, eIF3 p170 antibody, eIF3 p180 antibody, EIF3 p180 subunit antibody, eIF3 p185 antibody, eIF3 theta antibody, eIF3a antibody, EIF3A_HUMAN antibody, EIF3S10 antibody, eukaryotic translation initiation factor 3 subunit 10 (theta 150 170kD) antibody, eukaryotic translation initiation factor 3 subunit 10 (theta 170kD) antibody, eukaryotic translation initiation factor 3 subunit 10 170 kDa antibody, Eukaryotic translation initiation factor 3 subunit 10 antibody, eukaryotic translation initiation factor 3 subunit 10 theta 150 170 kDa antibody, Eukaryotic translation initiation factor 3 subunit A antibody, OTTHUMP00000020589 antibody, P167 antibody, p180 antibody, p185 antibody, TIF32 antibody

    UniProt

    Q14152

    途径

    Ribonucleoprotein Complex Subunit Organization
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