EDEM1 抗体 (AA 46-128)
Quick Overview for EDEM1 抗体 (AA 46-128) (ABIN7151970)
抗原
See all EDEM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 46-128
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human ER degradation-enhancing alpha-mannosidase-like protein 1 protein (46-128AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:200-1:500,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))
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别名
- EDEM1
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背景
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Background: Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2.
Aliases: EDEM1 antibody, EDEM antibody, KIAA0212ER degradation-enhancing alpha-mannosidase-like protein 1 antibody
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UniProt
- Q92611
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途径
- ER-Nucleus Signaling
抗原
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