Nth Endonuclease III-Like 1 (NTHL1) (AA 31-312) 抗体 (HRP)
Quick Overview for Nth Endonuclease III-Like 1 (NTHL1) (AA 31-312) 抗体 (HRP) (ABIN7151638)
抗原
See all Nth Endonuclease III-Like 1 (NTHL1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 31-312
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Endonuclease III-like protein 1 protein (31-312AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Nth Endonuclease III-Like 1 (NTHL1)
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别名
- NTHL1
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背景
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Background: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP-lyase activity cleaves the phosphodiester bond 3\' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. Has also 8-oxo-7,8-dihydroguanine (8-oxoG) DNA glycosylase activity. Acts preferentially on DNA damage opposite guanine residues in DNA. Is able to process lesions in nucleosomes without requiring or inducing nucleosome disruption.
Aliases: Bifunctional DNA N glycoslyase/DNA (apurinic or apyrimidinic site) lyase antibody, DNA glycoslyase/AP lyase antibody, Endonuclease III like protein 1 antibody, Endonuclease III-like protein 1 antibody, hNTH1 antibody, NTH 1 antibody, nth endonuclease III like 1 (E. coli) antibody, NTH endonuclease III Like 1 antibody, NTH1 antibody, NTHL 1 antibody, Nthl1 antibody, NTHL1_HUMAN antibody, OCTS 3 antibody, OCTS3 antibody
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UniProt
- P78549
抗原
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