TRIM25 抗体 (AA 81-272) (Biotin)
Quick Overview for TRIM25 抗体 (AA 81-272) (Biotin) (ABIN7151323)
抗原
See all TRIM25 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 81-272
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human E3 ubiquitin/ISG15 ligase TRIM25 protein (81-272AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TRIM25 (Tripartite Motif Containing 25 (TRIM25))
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别名
- TRIM25
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背景
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Background: Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates \'Lys-63\'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs. Mediates the ubiquitination and subsequent proteasomal degradation of ZFHX3 (PubMed:22452784).
Aliases: E3 ubiquitin/ISG15 ligase TRIM25 antibody, EFP antibody, Estrogen responsive finger protein antibody, Estrogen-responsive finger protein antibody, RING finger protein 147 antibody, RNF 147 antibody, RNF147 antibody, TRI25 antibody, TRI25_HUMAN antibody, TRIM 25 antibody, Trim25 antibody, Tripartite motif containing 25 antibody, Tripartite motif containing protein 25 antibody, Tripartite motif protein TRIM25 antibody, Tripartite motif-containing protein 25 antibody, Tripartite motifcontaining25 antibody, Ubiquitin/ISG15-conjugating enzyme TRIM25 antibody, Z147 antibody, Zinc finger protein 147 (estrogen responsive finger protein) antibody, Zinc finger protein 147 antibody, Zinc finger protein-147 antibody, ZNF 147 antibody, ZNF147 antibody
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UniProt
- Q14258
抗原
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