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TRIM25 抗体 (AA 81-272)

This anti-TRIM25 antibody is a 兔 多克隆 antibody detecting TRIM25 in WB, ELISA, IHC 和 IF. Suitable for 人.
产品编号 ABIN7151322
发货至: 中国
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Quick Overview for TRIM25 抗体 (AA 81-272) (ABIN7151322)

抗原

See all TRIM25 抗体
TRIM25 (Tripartite Motif Containing 25 (TRIM25))

适用

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宿主

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克隆类型

  • 81
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多克隆

标记

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This TRIM25 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 81-272

    原理

    TRIM25 Antibody

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human E3 ubiquitin/ISG15 ligase TRIM25 protein (81-272AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    TRIM25 (Tripartite Motif Containing 25 (TRIM25))

    别名

    TRIM25

    背景

    Background: Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates \\\'Lys-63\\\'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs. Mediates the ubiquitination and subsequent proteasomal degradation of ZFHX3 (PubMed:22452784).

    Aliases: E3 ubiquitin/ISG15 ligase TRIM25 antibody, EFP antibody, Estrogen responsive finger protein antibody, Estrogen-responsive finger protein antibody, RING finger protein 147 antibody, RNF 147 antibody, RNF147 antibody, TRI25 antibody, TRI25_HUMAN antibody, TRIM 25 antibody, Trim25 antibody, Tripartite motif containing 25 antibody, Tripartite motif containing protein 25 antibody, Tripartite motif protein TRIM25 antibody, Tripartite motif-containing protein 25 antibody, Tripartite motifcontaining25 antibody, Ubiquitin/ISG15-conjugating enzyme TRIM25 antibody, Z147 antibody, Zinc finger protein 147 (estrogen responsive finger protein) antibody, Zinc finger protein 147 antibody, Zinc finger protein-147 antibody, ZNF 147 antibody, ZNF147 antibody

    UniProt

    Q14258
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