TRIM11 抗体 (AA 267-468)
Quick Overview for TRIM11 抗体 (AA 267-468) (ABIN7151238)
抗原
See all TRIM11 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 267-468
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human E3 ubiquitin-protein ligase TRIM11 protein (267-468AA)
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亚型
- IgG
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anti-Tripartite Motif Containing 11 (TRIM11) (AA 383-432) antibody
TRIM11 适用: 人, 小鼠, 大鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 11 (TRIM11) (AA 249-263) antibodyVerified TRIM11 适用: 人 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Tripartite Motif Containing 11 (TRIM11) (C-Term) antibodyVerified TRIM11 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Tripartite Motif Containing 11 (TRIM11) (AA 267-468) antibodyTRIM11 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 11 (TRIM11) (AA 300-329), (C-Term) antibodyTRIM11 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33239 unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TRIM11 (Tripartite Motif Containing 11 (TRIM11))
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别名
- TRIM11
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背景
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Background: E3 ubiquitin-protein ligase that promotes the degradation of insoluble ubiquitinated proteins, including insoluble PAX6, poly-Gln repeat expanded HTT and poly-Ala repeat expanded ARX. Mediates PAX6 ubiquitination leading to proteasomal degradation, thereby modulating cortical neurogenesis. May also inhibit PAX6 transcriptional activity, possibly in part by preventing the binding of PAX6 to its consensus sequences. May contribute to the regulation of the intracellular level of HN (humanin) or HN-containing proteins through the proteasomal degradation pathway. Mediates MED15 ubiquitination leading to proteasomal degradation. May contribute to the innate restriction of retroviruses. Upon overexpression, reduces HIV-1 and murine leukemia virus infectivity, by suppressing viral gene expression. Antiviral activity depends on a functional E3 ubiquitin-protein ligase domain. May regulate TRIM5 turnover via the proteasome pathway, thus counteracting the TRIM5-mediated cross-species restriction of retroviral infection at early stages of the retroviral life cycle.
Aliases: BIA 1 antibody, BIA1 antibody, E3 ubiquitin protein ligase TRIM11 antibody, E3 ubiquitin-protein ligase TRIM11 antibody, Protein BIA1 antibody, RING finger protein 92 antibody, RING type E3 ubiquitin transferase TRIM11 antibody, RNF 92 antibody, RNF92 antibody, TRI11_HUMAN antibody, Trim 11 antibody, TRIM11 antibody, Tripartite motif containing 11 antibody, tripartite motif protein 11 antibody, Tripartite motif-containing protein 11 antibody
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UniProt
- Q96F44
抗原
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