SIAH2 抗体 (AA 1-72)
Quick Overview for SIAH2 抗体 (AA 1-72) (ABIN7151218)
抗原
See all SIAH2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-72
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human E3 ubiquitin-protein ligase SIAH2 protein (1-72AA)
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亚型
- IgG
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anti-Siah E3 Ubiquitin Protein Ligase 2 (SIAH2) (C-Term) antibody
SIAH2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Siah E3 Ubiquitin Protein Ligase 2 (SIAH2) (AA 216-244) antibodySIAH2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22563 unconjugated
anti-Siah E3 Ubiquitin Protein Ligase 2 (SIAH2) (C-Term) antibodySIAH2 适用: 人, 小鼠, 大鼠, 斑马鱼 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Siah E3 Ubiquitin Protein Ligase 2 (SIAH2) (C-Term) antibodySIAH2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Siah E3 Ubiquitin Protein Ligase 2 (SIAH2) (C-Term) antibodySIAH2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Siah E3 Ubiquitin Protein Ligase 2 (SIAH2) (N-Term) antibodySIAH2 适用: 人, 小鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Siah E3 Ubiquitin Protein Ligase 2 (SIAH2) (AA 215-264) antibodySIAH2 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, Pig, 豚鼠, 马, 兔, 猴, Bat, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Siah E3 Ubiquitin Protein Ligase 2 (SIAH2) (Middle Region) antibodySIAH2 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Siah E3 Ubiquitin Protein Ligase 2 (SIAH2) (AA 1-100), (N-Term) antibodySIAH2 适用: 人, Pig IHC, FACS, IF, ICC 宿主: 小鼠 Monoclonal 24E6H3 unconjugated
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应用备注
- Recommended dilution: IHC:1:500-1:1000, IF:1:200-1:500,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SIAH2 (Siah E3 Ubiquitin Protein Ligase 2 (SIAH2))
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别名
- SIAH2
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背景
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Background: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates E3 ubiquitin ligase activity either through direct binding to substrates or by functioning as the essential RING domain subunit of larger E3 complexes. Triggers the ubiquitin-mediated degradation of many substrates, including proteins involved in transcription regulation (POU2AF1, PML, NCOR1), a cell surface receptor (DCC), an antiapoptotic protein (BAG1), and a protein involved in synaptic vesicle function in neurons (SYP). Mediates ubiquitination and proteasomal degradation of DYRK2 in response to hypoxia. It is thereby involved in apoptosis, tumor suppression, cell cycle, transcription and signaling processes. Has some overlapping function with SIAH1. Triggers the ubiquitin-mediated degradation of TRAF2, whereas SIAH1 does not. Promotes monoubiquitination of SNCA.
Aliases: E3 ubiquitin-protein ligase Siah2 antibody, hSiah2 antibody, Seven in absentia homolog 2 antibody, Siah E3 ubiquitin protein ligase 2 antibody, Siah-2 antibody, siah2 antibody, SIAH2_HUMAN antibody, Ubiquitin Ligase Siah2 antibody
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UniProt
- O43255
抗原
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