RNF31 抗体 (AA 421-700) (FITC)
Quick Overview for RNF31 抗体 (AA 421-700) (FITC) (ABIN7151190)
抗原
See all RNF31 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 421-700
-
交叉反应
- 人
-
纯化方法
- >95%, Protein G purified
-
免疫原
- Recombinant Human E3 ubiquitin-protein ligase RNF31 protein (421-700AA)
-
亚型
- IgG
-
-
anti-Ring Finger Protein 31 (RNF31) (Middle Region) antibody
RNF31 适用: 人, 小鼠, 大鼠, 兔, 犬, 豚鼠, 马, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 31 (RNF31) (AA 955-983), (C-Term) antibodyRNF31 适用: 人 WB 宿主: 兔 Polyclonal RB39346 unconjugated
anti-Ring Finger Protein 31 (RNF31) (AA 421-700) antibodyRNF31 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 31 (RNF31) (C-Term) antibodyVerified RNF31 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Ring Finger Protein 31 (RNF31) antibodyRNF31 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 31 (RNF31) (C-Term) antibodyRNF31 适用: 人, 兔, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 31 (RNF31) (AA 500-700) antibodyRNF31 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
-
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- RNF31 (Ring Finger Protein 31 (RNF31))
-
别名
- RNF31
-
背景
-
Background: E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear (\\\'Met-1\\\'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis. Binds polyubiquitin of different linkage types.
Aliases: E3 ubiquitin protein ligase RNF31 antibody, FLJ10111 antibody, FLJ23501 antibody, HOIL 1L interacting protein antibody, HOIL-1-interacting protein antibody, HOIL1L interacting protein antibody, HOIP antibody, RING finger protein 31 antibody, RNF31 antibody, RNF31_HUMAN antibody, ZIBRA antibody, Zinc in between ring finger ubiquitin associated domain antibody, Zinc in-between-RING-finger ubiquitin-associated domain protein antibody
-
UniProt
- Q96EP0
抗原
-
