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RNF128 抗体 (AA 229-400)

This anti-RNF128 antibody is a 兔 多克隆 antibody detecting RNF128 in WB, ELISA 和 IF. Suitable for 人.
产品编号 ABIN7151138
发货至: 中国

Quick Overview for RNF128 抗体 (AA 229-400) (ABIN7151138)

抗原

See all RNF128 抗体
RNF128 (Ring Finger Protein 128 (RNF128))

适用

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宿主

  • 36

克隆类型

  • 36
多克隆

标记

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This RNF128 antibody is un-conjugated

应用范围

  • 31
  • 13
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Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 7
    • 6
    • 4
    • 2
    • 1
    AA 229-400

    交叉反应

    人, 小鼠

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human E3 ubiquitin-protein ligase RNF128 protein (229-400AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    RNF128 (Ring Finger Protein 128 (RNF128))

    别名

    RNF128

    背景

    Background: E3 ubiquitin-protein ligase that catalyzes \\\'Lys-48\\\'- and \\\'Lys-63\\\'-linked polyubiquitin chains formation. Functions as an inhibitor of cytokine gene transcription. Inhibits IL2 and IL4 transcription, thereby playing an important role in the induction of the anergic phenotype, a long-term stable state of T-lymphocyte unresponsiveness to antigenic stimulation associated with the blockade of interleukin production. Ubiquitinates ARPC5 with \\\'Lys-48\\\' linkages and COR1A with \\\'Lys-63\\\' linkages leading to their degradation, down-regulation of these cytosleletal components results in impaired lamellipodium formation and reduced accumulation of F-actin at the immunological synapse. Functions in the patterning of the dorsal ectoderm, sensitizes ectoderm to respond to neural-inducing signals.

    Aliases: E3 ubiquitin protein ligase RNF128 antibody, E3 ubiquitin-protein ligase RNF128 antibody, FLJ23516 antibody, Gene related to anergy in lymphocytes protein antibody, GRAIL antibody, RING finger protein 128 antibody, RN128_HUMAN antibody, RNF128 antibody

    UniProt

    Q8TEB7
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