我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

CBL 抗体 (AA 548-847)

Name: CBL 抗体 (AA 548-847)
Brand: antibodies-online
SKU: ABIN7150995
Availability: OutOfStock

This anti-CBL antibody is a 兔多克隆 antibody detecting CBL in WB, ELISA, IHC 和 IF. Suitable for 人.

Western Blot Positive WB detected in: Jurkat whole cell lysate, Raji whole cell lysate All lanes: CBL antibody at 3 μg/mL Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 100 kDa Observed band size: 100 kDa (CBL 抗体 (AA 548-847))

Immunofluorescent analysis of Hela cells using ABIN7150995 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) (CBL 抗体 (AA 548-847))

IHC image of ABIN7150995 diluted at 1:600 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. (CBL 抗体 (AA 548-847))

IHC

3 images

产品编号 ABIN7150995

发货至: 中国

Quick Overview for CBL 抗体 (AA 548-847) (ABIN7150995)

抗原

See all CBL 抗体

CBL (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))

适用

人

宿主

兔

克隆类型

多克隆

标记

This CBL antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Discover our top product CBL Primary Antibody

抗原表位
25

22

19

17

9

5

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 548-847

交叉反应

人

纯化方法

>95%, Protein G purified

免疫原

Recombinant Human E3 ubiquitin-protein ligase CBL protein (548-847AA)

亚型

IgG
anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) antibody
CBL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 3B12 unconjugated

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (AA 736-835) antibody
CBL 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 6D12 unconjugated

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (AA 1-906) antibody
CBL 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (AA 1-906) antibody
CBL 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (Internal Region) antibody
CBL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (pTyr770) antibody
CBL 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) antibody
CBL 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (pTyr674) antibody
CBL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (AA 637-906) antibody
CBL 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL) (pTyr674) antibody
CBL 适用: 人 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:50-1:200,

限制

仅限研究用
状态

Liquid

缓冲液

Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C,-80 °C

储存方法

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
抗原

CBL (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))

别名

CBL

背景

Background: Adapter protein that functions as a negative regulator of many signaling pathways that are triggered by activation of cell surface receptors. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Recognizes activated receptor tyrosine kinases, including KIT, FLT1, FGFR1, FGFR2, PDGFRA, PDGFRB, EGFR, CSF1R, EPHA8 and KDR and terminates signaling. Recognizes membrane-bound HCK, SRC and other kinases of the SRC family and mediates their ubiquitination and degradation. Participates in signal transduction in hematopoietic cells. Plays an important role in the regulation of osteoblast differentiation and apoptosis. Essential for osteoclastic bone resorption. The \\\'Tyr-731\\\' phosphorylated form induces the activation and recruitment of phosphatidylinositol 3-kinase to the cell membrane in a signaling pathway that is critical for osteoclast function. May be functionally coupled with the E2 ubiquitin-protein ligase UB2D3.
Aliases: 4732447J05Rik antibody, C CBL antibody, Cas Br M (murine) ecotropic retroviral transforming sequence antibody, Casitas B lineage lymphoma proto oncogene antibody, Casitas B-lineage lymphoma proto-oncogene antibody, CBL 2 antibody, cbl antibody, CBL_HUMAN antibody, CBL2 antibody, E3 ubiquitin protein ligase CBL antibody, E3 ubiquitin-protein ligase CBL antibody, Oncogene CBL2 antibody, Proto oncogene c CBL antibody, Proto-oncogene c-CBL antibody, RGD1561386 antibody, RING finger protein 55 antibody, RNF55 antibody, Signal transduction protein CBL antibody

UniProt

P22681

途径

TCR Signaling, Interferon-gamma Pathway, EGFR Signaling Pathway, EGFR Downregulation, VEGFR1 Specific Signals