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PIAS3 抗体 (AA 399-628)

This 兔 多克隆 anti-PIAS3 antibody specifically detects PIAS3 in IHC 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7150969
发货至: 中国
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Quick Overview for PIAS3 抗体 (AA 399-628) (ABIN7150969)

抗原

See all PIAS3 抗体
PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))

适用

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宿主

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克隆类型

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多克隆

标记

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This PIAS3 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    AA 399-628

    原理

    PIAS3 Antibody

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human E3 SUMO-protein ligase PIAS3 protein (399-628AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))

    别名

    PIAS3

    背景

    Background: Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth. Enhances the sumoylation of MTA1 and may participate in its paralog-selective sumoylation.

    Aliases: E3 SUMO protein ligase PIAS 3 antibody, E3 SUMO protein ligase PIAS3 antibody, E3 SUMO-protein ligase PIAS3 antibody, FLJ14651 antibody, OTTHUMP00000015586 antibody, OTTHUMP00000015587 antibody, PIAS 3 antibody, Pias3 antibody, PIAS3 protein antibody, PIAS3_HUMAN antibody, Protein inhibitor of activated STAT 3 antibody, Protein inhibitor of activated STAT protein 3 antibody, Protein inhibitor of activated STAT3 antibody, Zinc finger MIZ type containing 5 antibody, ZMIZ 5 antibody, ZMIZ5 antibody

    UniProt

    Q9Y6X2

    途径

    JAK/STAT Signaling
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