PIAS3 抗体 (AA 399-628)
Quick Overview for PIAS3 抗体 (AA 399-628) (ABIN7150969)
抗原
See all PIAS3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 399-628
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human E3 SUMO-protein ligase PIAS3 protein (399-628AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))
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别名
- PIAS3
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背景
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Background: Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth. Enhances the sumoylation of MTA1 and may participate in its paralog-selective sumoylation.
Aliases: E3 SUMO protein ligase PIAS 3 antibody, E3 SUMO protein ligase PIAS3 antibody, E3 SUMO-protein ligase PIAS3 antibody, FLJ14651 antibody, OTTHUMP00000015586 antibody, OTTHUMP00000015587 antibody, PIAS 3 antibody, Pias3 antibody, PIAS3 protein antibody, PIAS3_HUMAN antibody, Protein inhibitor of activated STAT 3 antibody, Protein inhibitor of activated STAT protein 3 antibody, Protein inhibitor of activated STAT3 antibody, Zinc finger MIZ type containing 5 antibody, ZMIZ 5 antibody, ZMIZ5 antibody
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UniProt
- Q9Y6X2
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途径
- JAK/STAT Signaling
抗原
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