DSCAM 抗体 (AA 1711-1867) (Biotin)
Quick Overview for DSCAM 抗体 (AA 1711-1867) (Biotin) (ABIN7150650)
抗原
See all DSCAM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1711-1867
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Down syndrome cell adhesion molecule protein (1711-1867AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- DSCAM (Down Syndrome Cell Adhesion Molecule (DSCAM))
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别名
- DSCAM
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背景
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Background: Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Mediates within retinal amacrine and ganglion cell subtypes both isoneuronal self-avoidance for creating an orderly dendritic arborization and heteroneuronal self-avoidance to maintain the mosaic spacing between amacrine and ganglion cell bodies (PubMed:10925149). Receptor for netrin required for axon guidance independently of and in collaboration with the receptor DCC. In spinal chord development plays a role in guiding commissural axons projection and pathfinding across the ventral midline to reach the floor plate upon ligand binding (PubMed:18585357, PubMed:19196994). Enhances netrin-induced phosphorylation of PAK1 and FYN (PubMed:15169762). Mediates intracellular signaling by stimulating the activation of MAPK8 and MAP kinase p38 (PubMed:18585357, PubMed:19196994). Adhesion molecule that promotes lamina-specific synaptic connections in the retina: expressed in specific subsets of interneurons and retinal ganglion cells (RGCs) and promotes synaptic connectivity via homophilic interactions (By similarity).
Aliases: CHD2 42 antibody, CHD2 52 antibody, CHD2 antibody, Down syndrome cell adhesion molecule antibody, DSCAM antibody, DSCAM_HUMAN antibody, human CHD2-52 down syndrome cell adhesion molecule 2, 9 antibody, OTTHUMP00000109193 2 antibody, SD11109p antibody
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UniProt
- O60469
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途径
- Regulation of Cell Size
抗原
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