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DSCAM 抗体 (AA 1711-1867)

This anti-DSCAM antibody is a 兔 多克隆 antibody detecting DSCAM in ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7150649
发货至: 中国
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Quick Overview for DSCAM 抗体 (AA 1711-1867) (ABIN7150649)

抗原

See all DSCAM 抗体
DSCAM (Down Syndrome Cell Adhesion Molecule (DSCAM))

适用

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宿主

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克隆类型

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多克隆

标记

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This DSCAM antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 1711-1867

    原理

    DSCAM Antibody

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Down syndrome cell adhesion molecule protein (1711-1867AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    DSCAM (Down Syndrome Cell Adhesion Molecule (DSCAM))

    别名

    DSCAM

    背景

    Background: Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Mediates within retinal amacrine and ganglion cell subtypes both isoneuronal self-avoidance for creating an orderly dendritic arborization and heteroneuronal self-avoidance to maintain the mosaic spacing between amacrine and ganglion cell bodies (PubMed:10925149). Receptor for netrin required for axon guidance independently of and in collaboration with the receptor DCC. In spinal chord development plays a role in guiding commissural axons projection and pathfinding across the ventral midline to reach the floor plate upon ligand binding (PubMed:18585357, PubMed:19196994). Enhances netrin-induced phosphorylation of PAK1 and FYN (PubMed:15169762). Mediates intracellular signaling by stimulating the activation of MAPK8 and MAP kinase p38 (PubMed:18585357, PubMed:19196994). Adhesion molecule that promotes lamina-specific synaptic connections in the retina: expressed in specific subsets of interneurons and retinal ganglion cells (RGCs) and promotes synaptic connectivity via homophilic interactions (By similarity).

    Aliases: CHD2 42 antibody, CHD2 52 antibody, CHD2 antibody, Down syndrome cell adhesion molecule antibody, DSCAM antibody, DSCAM_HUMAN antibody, human CHD2-52 down syndrome cell adhesion molecule 2, 9 antibody, OTTHUMP00000109193 2 antibody, SD11109p antibody

    UniProt

    O60469

    途径

    Regulation of Cell Size
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