DMRT1 抗体 (AA 195-363)
Quick Overview for DMRT1 抗体 (AA 195-363) (ABIN7150637)
抗原
See all DMRT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 195-363
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原理
- DMRT1 Antibody
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交叉反应
- 小鼠
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Human Doublesex- and mab-3-related transcription factor 1 protein (195-363AA)
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亚型
- IgG
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anti-Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1) (AA 1-373) antibody
DMRT1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G11 unconjugated
anti-Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1) (AA 134-373) antibodyDMRT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1) (AA 1-373) antibodyDMRT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1) (AA 1-373) antibodyDMRT1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1) (N-Term) antibodyDMRT1 适用: 人, Cow, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1) antibodyDMRT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1) (AA 98-128), (N-Term) antibodyDMRT1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))
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别名
- DMRT1
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背景
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Background: Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and promotes spermatogonial development by activating spermatogonial differentiation genes, such as SOHLH1. Also plays a key role in postnatal sex maintenance by maintaining testis determination and preventing feminization: represses transcription of female promoting genes such as FOXL2 and activates male-specific genes. May act as a tumor suppressor. May also play a minor role in oogenesis (By similarity).
Aliases: CT154 antibody, DM domain expressed in testis 1 antibody, DM domain expressed in testis protein 1 antibody, DM domain gene expressed in testis antibody, DMRT 1 antibody, dmrt1 antibody, DMRT1_HUMAN antibody, DMT 1 antibody, DMT1 antibody, Doublesex and mab 3 related transcription factor 1 antibody, Doublesex- and mab-3-related transcription factor 1 antibody
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UniProt
- Q9Y5R6
抗原
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