CCDC111 抗体 (AA 305-537) (Biotin)
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北京 101111
Quick Overview for CCDC111 抗体 (AA 305-537) (Biotin) (ABIN7150407)
抗原
See all CCDC111 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 305-537
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原理
- PRIMPOL Antibody, Biotin conjugated
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Human DNA-directed primase/polymerase protein (305-537AA)
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亚型
- IgG
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anti-Coiled-Coil Domain Containing 111 (CCDC111) antibody
CCDC111 适用: 人, 小鼠, 大鼠 IHC, IF, WB 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 111 (CCDC111) (AA 305-537) antibodyCCDC111 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CCDC111 (Coiled-Coil Domain Containing 111 (CCDC111))
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别名
- PRIMPOL
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背景
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Background: DNA primase and DNA polymerase able to initiate de novo DNA synthesis using dNTPs. Shows a high capacity to tolerate DNA damage lesions such as 8oxoG and abasic sites in DNA. Involved in translesion synthesis via its primase activity by mediating uninterrupted fork progression after programmed or damage-induced fork arrest and by reinitiating DNA synthesis after dNTP depletion. Required for mitochondrial DNA (mtDNA) synthesis, suggesting it may be involved in DNA tolerance during the replication of mitochondrial DNA. Has non-overlapping function with POLH.
Aliases: CC111_HUMAN antibody, CCDC111 antibody, Coiled coil domain containing 111 antibody, Coiled-coil domain-containing protein 111 antibody, DNA-directed primase/polymerase protein antibody, MYP22 antibody, Primase and polymerase (DNA directed) antibody, PRIMPOL antibody
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UniProt
- Q96LW4
抗原
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