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MCM8 抗体 (AA 1-67) (HRP)

This anti-MCM8 antibody (ABIN7150184) is a Rabbit Polyclonal antibody detecting MCM8 in ELISA. Suitable for Human.
产品编号 ABIN7150184
发货至: 中国

Quick Overview for MCM8 抗体 (AA 1-67) (HRP) (ABIN7150184)

抗原

See all MCM8 抗体
MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))

适用

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宿主

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克隆类型

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多克隆

标记

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This MCM8 antibody is conjugated to HRP

应用范围

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ELISA
  • 抗原表位

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    AA 1-67

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human DNA helicase MCM8 protein (1-67AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))

    别名

    MCM8

    背景

    Background: Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8-MCM9 complex probably acts as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51 and is required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart. May also play a non-essential for DNA replication: may be involved in the activation of the prereplicative complex (pre-RC) during G(1) phase by recruiting CDC6 to the origin recognition complex (ORC). Binds chromatin throughout the cell cycle.

    Aliases: C20orf154 antibody, dJ967N21.5 antibody, DNA helicase MCM8 antibody, DNA replication licensing factor MCM8 antibody, MCM8 antibody, MCM8_HUMAN antibody, MGC119522 antibody, MGC119523 antibody, MGC12866 antibody, MGC4816 antibody, Minichromosome maintenance 8 antibody, Minichromosome maintenance complex component 8 antibody, REC antibody

    UniProt

    Q9UJA3

    途径

    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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