DNMT3A 抗体 (AA 680-902)
Quick Overview for DNMT3A 抗体 (AA 680-902) (ABIN7150112)
抗原
See all DNMT3A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 680-902
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human DNA (cytosine-5)-methyltransferase 3A protein (680-902AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
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别名
- DNMT3A
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背景
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Background: Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZNF238. Can actively repress transcription through the recruitment of HDAC activity
Aliases: DNA (cytosine 5) methyltransferase 3 alpha antibody, DNA (cytosine 5) methyltransferase 3A antibody, DNA (cytosine-5)-methyltransferase 3A antibody, DNA cytosine methyltransferase 3A2 antibody, DNA methyltransferase 3 alpha antibody, DNA methyltransferase 3a antibody, DNA methyltransferase HsaIIIA antibody, DNA MTase HsaIIIA antibody, DNM3A_HUMAN antibody, DNMT 3a antibody, DNMT antibody, Dnmt3a antibody, DNMT3A2 antibody, M.HsaIIIA antibody, MCMT antibody, OTTHUMP00000201149 antibody, TBRS antibody
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UniProt
- Q9Y6K1
抗原
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