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DISC1 抗体 (AA 99-325) (FITC)

This anti-DISC1 antibody is a 兔 多克隆 antibody detecting DISC1 in . Suitable for 人.
产品编号 ABIN7150094
发货至: 中国

Quick Overview for DISC1 抗体 (AA 99-325) (FITC) (ABIN7150094)

抗原

See all DISC1 抗体
DISC1 (Disrupted in Schizophrenia 1 (DISC1))

适用

  • 71
  • 24
  • 16
  • 1

宿主

  • 74
  • 4
  • 1
  • 1

克隆类型

  • 75
  • 7
多克隆

标记

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  • 4
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  • 2
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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This DISC1 antibody is conjugated to FITC

应用范围

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  • 抗原表位

    • 15
    • 7
    • 6
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    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 99-325

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Disrupted in schizophrenia 1 protein (99-325AA)

    亚型

    IgG
  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    DISC1 (Disrupted in Schizophrenia 1 (DISC1))

    别名

    DISC1

    背景

    Background: Involved in the regulation of multiple aspects of embryonic and adult neurogenesis. Required for neural progenitor proliferation in the ventrical/subventrical zone during embryonic brain development and in the adult dentate gyrus of the hippocampus. Participates in the Wnt-mediated neural progenitor proliferation as a positive regulator by modulating GSK3B activity and CTNNB1 abundance. Plays a role as a modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including neuron positioning, dendritic development and synapse formation. Inhibits the activation of AKT-mTOR signaling upon interaction with CCDC88A. Regulates the migration of early-born granule cell precursors toward the dentate gyrus during the hippocampal development. Plays a role, together with PCNT, in the microtubule network formation.

    Aliases: C1orf136 antibody, DISC1 antibody, DISC1_HUMAN antibody, Disrupted in schizophrenia 1 antibody, Disrupted in schizophrenia 1 protein antibody, KIAA0457 antibody, RP4-730B13.1 antibody, SCZD9 antibody

    UniProt

    Q9NRI5

    途径

    Regulation of Cell Size
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