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DIS3L2 抗体 (AA 201-400)

This 兔 多克隆 anti-DIS3L2 antibody specifically detects DIS3L2 in ELISA 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7150017
发货至: 中国
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Quick Overview for DIS3L2 抗体 (AA 201-400) (ABIN7150017)

抗原

See all DIS3L2 抗体
DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))

适用

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宿主

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克隆类型

  • 29
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多克隆

标记

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This DIS3L2 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 201-400

    原理

    DIS3L2 Antibody

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human DIS3-like exonuclease 2 protein (201-400AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))

    别名

    DIS3L2

    背景

    Background: 3\'-5\'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3\' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3\'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation.

    Aliases: DI3L2_HUMAN antibody, DIS3 L2 antibody, DIS3 mitotic control homolog (S. cerevisiae) like 2 antibody, DIS3 mitotic control homolog like 2 antibody, DIS3-like exonuclease 2 antibody, Dis3l2 antibody, FLJ36974 antibody, MGC42174 antibody

    UniProt

    Q8IYB7

    途径

    Stem Cell Maintenance
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