SAMHD1 抗体 (AA 1-314) (FITC)
Quick Overview for SAMHD1 抗体 (AA 1-314) (FITC) (ABIN7149716)
抗原
See all SAMHD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-314
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交叉反应
- 人
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纯化方法
- >95%, Antigen Affinity purified & Affinity purified
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免疫原
- Recombinant Human Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 protein (1-314AA)
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亚型
- IgG
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))
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别名
- SAMHD1
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背景
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Background: Host restriction nuclease involved in defense response to virus. Has dNTPase activity and reduces cellular dNTP levels to levels too low for retroviral reverse transcription to occur. Blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May play a role in mediating proinflammatory responses to TNF-alpha signaling (PubMed:18546154, PubMed:19525956, PubMed:22056990, PubMed:24336198, PubMed:28229507). Has ribonuclease activity, acting on single-stranded RNA. This activity is essential for H1V-1 restriction (PubMed:25038827).
Aliases: CHBL2 antibody, DCIP antibody, Dendritic cell derived IFNG induced protein antibody, Dendritic cell-derived IFNG-induced protein antibody, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 antibody, dNTPase antibody, HD domain containing 1 antibody, HDDC1 antibody, Mg11 antibody, Monocyte protein 5 antibody, MOP 5 antibody, MOP-5 antibody, MOP5 antibody, OTTHUMP00000030889 antibody, SAM domain and HD domain 1 antibody, SAM domain and HD domain containing protein 1 antibody, SAM domain and HD domain-containing protein 1 antibody, SAMH1_HUMAN antibody, Samhd1 antibody, SBBI88 antibody
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UniProt
- Q9Y3Z3
抗原
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