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SAMHD1 抗体 (AA 1-314)

This anti-SAMHD1 antibody is a 兔 多克隆 antibody detecting SAMHD1 in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7149714
发货至: 中国

Quick Overview for SAMHD1 抗体 (AA 1-314) (ABIN7149714)

抗原

See all SAMHD1 抗体
SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

适用

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宿主

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克隆类型

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  • 16
多克隆

标记

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This SAMHD1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 15
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    AA 1-314

    交叉反应

    纯化方法

    >95%, Antigen Affinity purified & Affinity purified

    免疫原

    Recombinant Human Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 protein (1-314AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:1000-1:5000, IHC:1:100-1:500,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

    别名

    SAMHD1

    背景

    Background: Host restriction nuclease involved in defense response to virus. Has dNTPase activity and reduces cellular dNTP levels to levels too low for retroviral reverse transcription to occur. Blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May play a role in mediating proinflammatory responses to TNF-alpha signaling (PubMed:18546154, PubMed:19525956, PubMed:22056990, PubMed:24336198, PubMed:28229507). Has ribonuclease activity, acting on single-stranded RNA. This activity is essential for H1V-1 restriction (PubMed:25038827).

    Aliases: CHBL2 antibody, DCIP antibody, Dendritic cell derived IFNG induced protein antibody, Dendritic cell-derived IFNG-induced protein antibody, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 antibody, dNTPase antibody, HD domain containing 1 antibody, HDDC1 antibody, Mg11 antibody, Monocyte protein 5 antibody, MOP 5 antibody, MOP-5 antibody, MOP5 antibody, OTTHUMP00000030889 antibody, SAM domain and HD domain 1 antibody, SAM domain and HD domain containing protein 1 antibody, SAM domain and HD domain-containing protein 1 antibody, SAMH1_HUMAN antibody, Samhd1 antibody, SBBI88 antibody

    UniProt

    Q9Y3Z3
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