DOCK7 抗体 (AA 1440-1671)
Quick Overview for DOCK7 抗体 (AA 1440-1671) (ABIN7149599)
抗原
See all DOCK7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1440-1671
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Dedicator of cytokinesis protein 7 protein (1440-1671AA)
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亚型
- IgG
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anti-Dedicator of Cytokinesis 7 (DOCK7) (N-Term) antibody
DOCK7 适用: 人, 大鼠, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Dedicator of Cytokinesis 7 (DOCK7) (AA 1-624) antibodyDOCK7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:2000-1:5000, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))
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别名
- DOCK7
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背景
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Background: Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 \\\'Ser-15\\\' phosphorylation during axon formation and consequently for neuronal polarization (PubMed:16982419). Has a role in pigmentation (By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation, negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3 (By similarity).
Aliases: DOCK7 antibody, KIAA1771Dedicator of cytokinesis protein 7 antibody
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UniProt
- Q96N67
抗原
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