DAPK2 抗体 (AA 222-370) (Biotin)
Quick Overview for DAPK2 抗体 (AA 222-370) (Biotin) (ABIN7149555)
抗原
See all DAPK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 222-370
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Death-associated protein kinase 2 protein (222-370AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- DAPK2 (Death-Associated Protein Kinase 2 (DAPK2))
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别名
- DAPK2
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背景
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Background: Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation. Isoform 2 is not regulated by calmodulin. It can phosphorylate MYL9. It can induce membrane blebbing and autophagic cell death.
Aliases: DAK2 antibody, DAP kinase 2 antibody, DAP kinase related protein 1 antibody, DAP kinase related protein 1 beta isoform antibody, DAP-kinase-related protein 1 antibody, DAPK2 antibody, DAPK2_HUMAN antibody, Death associated protein kinase 2 antibody, Death-associated protein kinase 2 antibody, DRP 1 antibody, DRP-1 antibody, DRP1 antibody, MGC119312 antibody
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UniProt
- Q9UIK4
抗原
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