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NCK1 抗体 (AA 58-377)

This 兔 多克隆 anti-NCK1 antibody specifically detects NCK1 in WB, IHC 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7149352
发货至: 中国
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Quick Overview for NCK1 抗体 (AA 58-377) (ABIN7149352)

抗原

See all NCK1 抗体
NCK1 (NCK Adaptor Protein 1 (NCK1))

适用

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宿主

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克隆类型

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多克隆

标记

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This NCK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    AA 58-377

    原理

    NCK1 Antibody

    交叉反应

    大鼠

    纯化方法

    Antigen Affinity purified

    免疫原

    Recombinant Human Cytoplasmic protein NCK1 protein (58-377AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    NCK1 (NCK Adaptor Protein 1 (NCK1))

    别名

    NCK1

    背景

    Background: Adapter protein which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in the DNA damage response, not in the detection of the damage by ATM/ATR, but for efficient activation of downstream effectors, such as that of CHEK2. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling. Modulates the activation of EIF2AK2/PKR by dsRNA. May play a role in cell adhesion and migration through interaction with ephrin receptors.

    Aliases: Cytoplasmic protein NCK1 antibody, Melanoma Nck protein antibody, MGC12668 antibody, NCK 1 antibody, NCK adaptor protein 1 antibody, NCK alpha antibody, NCK antibody, NCK tyrosine kinase antibody, Nck-1 antibody, NCK1 antibody, NCK1_HUMAN antibody, NCKalpha antibody, Non catalytic region of tyrosine kinase antibody, SH2/SH3 adaptor protein NCK alpha antibody, SH2/SH3 adaptor protein NCK-alpha antibody

    UniProt

    P16333

    途径

    TCR Signaling, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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