CPEB4 抗体 (AA 244-515) (Biotin)
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北京 101111
Quick Overview for CPEB4 抗体 (AA 244-515) (Biotin) (ABIN7149349)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 244-515
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原理
- CPEB4 Antibody, Biotin conjugated
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Human Cytoplasmic polyadenylation element-binding protein 4 protein (244-515AA)
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亚型
- IgG
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anti-Cytoplasmic Polyadenylation Element Binding Protein 4 (CPEB4) (N-Term) antibody
CPEB4 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 兔, Cow, 马, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
anti-Cytoplasmic Polyadenylation Element Binding Protein 4 (CPEB4) (AA 244-515) antibodyCPEB4 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytoplasmic Polyadenylation Element Binding Protein 4 (CPEB4) (AA 109-137), (N-Term) antibodyCPEB4 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB27196 unconjugated
anti-Cytoplasmic Polyadenylation Element Binding Protein 4 (CPEB4) (AA 72-121) antibodyCPEB4 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 兔, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Cytoplasmic Polyadenylation Element Binding Protein 4 (CPEB4) (N-Term) antibodyCPEB4 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CPEB4 (Cytoplasmic Polyadenylation Element Binding Protein 4 (CPEB4))
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别名
- CPEB4
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背景
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Background: Sequence-specific RNA-binding protein that binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5\\\'-UUUUUAU-3\\\') within the mRNA 3\\\'-UTR (PubMed:24990967). RNA binding results in a clear conformational change analogous to the Venus fly trap mechanism (PubMed:24990967). Regulates activation of unfolded protein response (UPR) in the process of adaptation to ER stress in liver, by maintaining translation of CPE-regulated mRNAs in conditions in which global protein synthesis is inhibited (By similarity). Required for cell cycle progression, specifically for cytokinesis and chromosomal segregation (PubMed:26398195). Plays a role as an oncogene promoting tumor growth and progression by positively regulating translation of t-plasminogen activator/PLAT (PubMed:22138752). Stimulates proliferation of melanocytes (PubMed:27857118). In contrast to CPEB1 and CPEB3, does not play role in synaptic plasticity, learning and memory (By similarity).
Aliases: CPE binding protein 4 antibody, CPE-binding protein 4 antibody, CPE-BP4 antibody, cpeb4 antibody, CPEB4_HUMAN antibody, Cytoplasmic polyadenylation element binding protein 4 antibody, Cytoplasmic polyadenylation element-binding protein 4 antibody, hCPEB-4 antibody, KIAA1673 antibody
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UniProt
- Q17RY0
抗原
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