CTH 抗体 (AA 1-70)
Quick Overview for CTH 抗体 (AA 1-70) (ABIN7148969)
抗原
See all CTH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-70
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Cystathionine gamma-lyase protein (1-70AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))
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别名
- CTH
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背景
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Background: Catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure. Acts as a cysteine-protein sulfhydrase by mediating sulfhydration of target proteins: sulfhydration consists of converting -SH groups into -SSH on specific cysteine residues of target proteins such as GAPDH, PTPN1 and NF-kappa-B subunit RELA, thereby regulating their function.
Aliases: CGL_HUMAN antibody, CTH antibody, cystathionase (cystathionine gamma-lyase) antibody, Cystathionine gamma lyase antibody, Cystathionine gamma-lyase antibody, Cysteine desulfhydrase antibody, Gamma cystathionase antibody, Gamma-cystathionase antibody, Homoserine deaminase antibody, Homoserine dehydratase antibody, MGC9471 antibody
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UniProt
- P32929
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途径
- ER-Nucleus Signaling, Warburg Effect
抗原
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