CDK13 抗体 (AA 1-170) (FITC)
Quick Overview for CDK13 抗体 (AA 1-170) (FITC) (ABIN7148857)
抗原
See all CDK13 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-170
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Cyclin-dependent kinase 13 protein (1-170AA)
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亚型
- IgG
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CDK13 (Cyclin-Dependent Kinase 13 (CDK13))
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别名
- CDK13
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背景
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Background: Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at \'Lys-50\' and \'Lys-51\', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef.
Aliases: CDC2 related protein kinase 5 antibody, CDC2-related protein kinase 5 antibody, CDC2L antibody, CDK13 antibody, CDK13_HUMAN antibody, cell division controller cholinesterase related antibody, cell division cycle 2 like 5 (cholinesterase related cell division controller) antibody, cell division cycle 2 like 5 antibody, Cell division cycle 2 like protein kinase 5 antibody, Cell division cycle 2-like protein kinase 5 antibody, Cell division protein kinase 13 antibody, CHED antibody, Cholinesterase related cell division controller antibody, Cholinesterase-related cell division controller antibody, cyclin dependent kinase 13 antibody, Cyclin-dependent kinase 13 antibody, hCDK13 antibody
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UniProt
- Q14004
抗原
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