CREB3L1 抗体 (AA 396-500) (Biotin)
Quick Overview for CREB3L1 抗体 (AA 396-500) (Biotin) (ABIN7148817)
抗原
See all CREB3L1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 396-500
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Cyclic AMP-responsive element-binding protein 3-like protein 1 protein (396-500AA)
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亚型
- IgG
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anti-CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1) (AA 396-500) antibody
CREB3L1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1) (C-Term) antibodyVerified CREB3L1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1) (AA 481-509), (C-Term) antibodyCREB3L1 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB19585 unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1) (AA 1-519) antibodyCREB3L1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1) (N-Term) antibodyCREB3L1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1) (C-Term) antibodyCREB3L1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1) antibodyCREB3L1 适用: 人, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1) (AA 488-517), (C-Term) antibodyCREB3L1 适用: 人, 小鼠 WB, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1) (AA 1-294) antibodyCREB3L1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1) (AA 1-519) antibodyCREB3L1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))
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别名
- CREB3L1
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背景
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Background: Transcription factor involved in unfolded protein response (UPR). In the absence of endoplasmic reticulum (ER) stress, inserted into ER membranes, with N-terminal DNA-binding and transcription activation domains oriented toward the cytosolic face of the membrane. In response to ER stress, transported to the Golgi, where it is cleaved in a site-specific manner by resident proteases S1P/MBTPS1 and S2P/MBTPS2. The released N-terminal cytosolic domain is translocated to the nucleus to effect transcription of specific target genes. Plays a critical role in bone formation through the transcription of COL1A1, and possibly COL1A2, and the secretion of bone matrix proteins. Directly binds to the UPR element (UPRE)-like sequence in an osteoblast-specific COL1A1 promoter region and induces its transcription. Does not regulate COL1A1 in other tissues, such as skin (By similarity). Required to protect astrocytes from ER stress-induced cell death. In astrocytes, binds to the cAMP response element (CRE) of the BiP/HSPA5 promoter and participate in its transcriptional activation (By similarity). May play a role in limiting virus spread by inhibiting proliferation of virus-infected cells. Upon infection with diverse DNA and RNA viruses, inhibits cell-cycle progression by binding to promoters and activating transcription of genes encoding cell-cycle inhibitors, such as p21/CDKN1A (PubMed:21767813). Binds the DNA consensus sequence 5\'-GTGXGCXGC-3\' (PubMed:21767813).
Aliases: BBF-2 homolog antibody, CAMP responsive element binding protein 3 like 1 antibody, cAMP-responsive element-binding protein 3-like protein 1 antibody, CR3L1_HUMAN antibody, Creb3l1 antibody, Cyclic AMP responsive element binding protein 3 like protein 1 antibody, OASIS antibody, Old astrocyte specifically-induced substance antibody, Processed cyclic AMP-responsive element-binding protein 3-like protein 1 antibody
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UniProt
- Q96BA8
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途径
- Thyroid Hormone Synthesis, Chromatin Binding
抗原
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