Cullin 5 抗体 (AA 1-300)
Quick Overview for Cullin 5 抗体 (AA 1-300) (ABIN7148758)
抗原
See all Cullin 5 (CUL5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-300
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Cullin-5 protein (1-300AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Cullin 5 (CUL5)
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别名
- CUL5
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背景
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Background: Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.
Aliases: CUL 5 antibody, CUL-5 antibody, CUL5 antibody, CUL5_HUMAN antibody, Cullin 5 antibody, Cullin-5 (vasopressin-activated calcium-mobilizing receptor-1) antibody, Cullin-5 antibody, Cullin5 antibody, VACM 1 antibody, VACM-1 antibody, VACM1 antibody, Vasopressin activated calcium mobilizing receptor 1 antibody, Vasopressin activated calcium mobilizing receptor antibody, Vasopressin-activated calcium-mobilizing receptor 1 antibody, Vasopressin-activated calcium-mobilizing receptor-1 antibody
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UniProt
- Q93034
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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