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Cullin 5 抗体 (AA 1-300)

The 兔 多克隆 anti-Cullin 5 antibody (ABIN7148758) specifically detects Cullin 5 in ELISA 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7148758
发货至: 中国
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Quick Overview for Cullin 5 抗体 (AA 1-300) (ABIN7148758)

抗原

See all Cullin 5 (CUL5) 抗体
Cullin 5 (CUL5)

适用

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宿主

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克隆类型

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多克隆

标记

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This Cullin 5 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 1-300

    原理

    CUL5 Antibody

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Cullin-5 protein (1-300AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Cullin 5 (CUL5)

    别名

    CUL5

    背景

    Background: Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.

    Aliases: CUL 5 antibody, CUL-5 antibody, CUL5 antibody, CUL5_HUMAN antibody, Cullin 5 antibody, Cullin-5 (vasopressin-activated calcium-mobilizing receptor-1) antibody, Cullin-5 antibody, Cullin5 antibody, VACM 1 antibody, VACM-1 antibody, VACM1 antibody, Vasopressin activated calcium mobilizing receptor 1 antibody, Vasopressin activated calcium mobilizing receptor antibody, Vasopressin-activated calcium-mobilizing receptor 1 antibody, Vasopressin-activated calcium-mobilizing receptor-1 antibody

    UniProt

    Q93034

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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