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CRTC2 抗体 (AA 180-372)

This anti-CRTC2 antibody is a 兔 多克隆 antibody detecting CRTC2 in ELISA, IHC 和 IF. Suitable for 人.
产品编号 ABIN7148679
发货至: 中国

Quick Overview for CRTC2 抗体 (AA 180-372) (ABIN7148679)

抗原

See all CRTC2 抗体
CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

适用

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宿主

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克隆类型

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  • 9
多克隆

标记

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This CRTC2 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 180-372

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human CREB-regulated transcription coactivator 2 protein (180-372AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

    别名

    CRTC2

    背景

    Background: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 \'Ser-133\' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).

    Aliases: CREB regulated transcription coactivator 2 antibody, CREB-regulated transcription coactivator 2 antibody, CRTC2 antibody, CRTC2_HUMAN antibody, RP11-422P24.6 antibody, TORC-2 antibody, torc2 antibody, Transducer of CREB protein 2 antibody, Transducer of regulated cAMP response element-binding protein antibody, Transducer of regulated cAMP response element-binding protein (CREB) 2 antibody, Transducer of regulated cAMP response element-binding protein 2 antibody, Transducer of regulated CREB protein 2 antibody

    UniProt

    Q53ET0

    途径

    AMPK Signaling, Carbohydrate Homeostasis
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