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CLASP2 抗体 (AA 226-381) (HRP)

This anti-CLASP2 antibody is a 兔 多克隆 antibody detecting CLASP2 in ELISA. Suitable for 人.
产品编号 ABIN7147939
发货至: 中国

Quick Overview for CLASP2 抗体 (AA 226-381) (HRP) (ABIN7147939)

抗原

See all CLASP2 抗体
CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))

适用

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宿主

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克隆类型

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多克隆

标记

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This CLASP2 antibody is conjugated to HRP

应用范围

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ELISA
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    AA 226-381

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human CLIP-associating protein 2 protein (226-381AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))

    别名

    CLASP2

    背景

    Background: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules (PubMed:26003921). Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2 (PubMed:16824950). This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle (PubMed:16866869, PubMed:16914514). Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.

    Aliases: CLAP2_HUMAN antibody, CLASP 2 antibody, Clasp2 antibody, CLIP associating protein 2 antibody, CLIP-associating protein 2 antibody, Cytoplasmic linker associated protein 2 antibody, Cytoplasmic linker-associated protein 2 antibody, hOrbit2 antibody, KIAA0627 antibody, Multiple asters (Mast) like homolog 2 antibody, Protein Orbit homolog 2 antibody

    UniProt

    O75122

    途径

    Microtubule Dynamics, Maintenance of Protein Location
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