BHLHE40 抗体 (AA 184-302)
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北京 101111
Quick Overview for BHLHE40 抗体 (AA 184-302) (ABIN7147837)
抗原
See all BHLHE40 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 184-302
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原理
- BHLHE40 Antibody
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Human Class E basic helix-loop-helix protein 40 protein (184-302AA)
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亚型
- IgG
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anti-Basic Helix-Loop-Helix Family, Member E40 (BHLHE40) (AA 130-229) antibody
BHLHE40 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5B1 unconjugated
anti-Basic Helix-Loop-Helix Family, Member E40 (BHLHE40) (AA 173-412) antibodyBHLHE40 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Basic Helix-Loop-Helix Family, Member E40 (BHLHE40) (N-Term) antibodyBHLHE40 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Basic Helix-Loop-Helix Family, Member E40 (BHLHE40) (Middle Region) antibodyBHLHE40 适用: 人, 小鼠, 大鼠, Cow, 绵羊, 豚鼠, 马, 犬, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Basic Helix-Loop-Helix Family, Member E40 (BHLHE40) antibodyBHLHE40 适用: 人, 小鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Basic Helix-Loop-Helix Family, Member E40 (BHLHE40) (AA 130-229) antibodyBHLHE40 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Basic Helix-Loop-Helix Family, Member E40 (BHLHE40) (AA 249-298) antibodyBHLHE40 适用: 人, 小鼠, 大鼠, 豚鼠, 马, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Basic Helix-Loop-Helix Family, Member E40 (BHLHE40) (AA 22-51), (N-Term) antibodyBHLHE40 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB28435 unconjugated
anti-Basic Helix-Loop-Helix Family, Member E40 (BHLHE40) (C-Term) antibodyBHLHE40 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- BHLHE40 (Basic Helix-Loop-Helix Family, Member E40 (BHLHE40))
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别名
- BHLHE40
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背景
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Background: Transcriptional repressor involved in the regulation of the circadian rhythm by negatively regulating the activity of the clock genes and clock-controlled genes. Acts as the negative limb of a novel autoregulatory feedback loop (DEC loop) which differs from the one formed by the PER and CRY transcriptional repressors (PER/CRY loop). Both these loops are interlocked as it represses the expression of PER1/2 and in turn is repressed by PER1/2 and CRY1/2. Represses the activity of the circadian transcriptional activator: CLOCK-ARNTL/BMAL1|ARNTL2/BMAL2 heterodimer by competing for the binding to E-box elements (5\\\'-CACGTG-3\\\') found within the promoters of its target genes. Negatively regulates its own expression and the expression of DBP and BHLHE41/DEC2. Acts as a corepressor of RXR and the RXR-LXR heterodimers and represses the ligand-induced RXRA and NR1H3/LXRA transactivation activity. May be involved in the regulation of chondrocyte differentiation via the cAMP pathway.
Aliases: BHE40_HUMAN antibody, bHLHB2 antibody, bHLHe40 antibody, Class B Basic Helix Loop Helix Protein 2 antibody, Class B basic helix-loop-helix protein 2 antibody, Class E basic helix loop helix protein 40 antibody, Class E basic helix-loop-helix protein 40 antibody, Clast5 antibody, DEC1 antibody, Differentially expressed in chondrocytes protein 1 antibody, E47 interaction protein 1 antibody, EIP1 antibody, Enhancer of split and hairy related protein 2 antibody, Enhancer-of-split and hairy-related protein 2 antibody, SHARP 2 antibody, SHARP-2 antibody, Stimulated by retinoic acid gene 13 protein antibody, STRA13 antibody
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UniProt
- O14503
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途径
- Photoperiodism
抗原
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