CHD5 抗体 (AA 1600-1699)
Quick Overview for CHD5 抗体 (AA 1600-1699) (ABIN7147724)
抗原
See all CHD5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1600-1699
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Chromodomain-helicase-DNA-binding protein 5 protein (1600-1699AA)
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亚型
- IgG
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anti-Chromodomain Helicase DNA Binding Protein 5 (CHD5) (C-Term) antibody
CHD5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 5 (CHD5) (Internal Region) antibodyVerified CHD5 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 5 (CHD5) (C-Term) antibodyCHD5 适用: 人, 小鼠 WB, IF, ICC 宿主: 大鼠 Monoclonal 5A10 unconjugated
anti-Chromodomain Helicase DNA Binding Protein 5 (CHD5) (Internal Region) antibodyCHD5 适用: 人 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 5 (CHD5) (AA 64-98) antibodyCHD5 适用: 人 WB 宿主: 兔 Polyclonal RB54755 unconjugated
anti-Chromodomain Helicase DNA Binding Protein 5 (CHD5) (AA 712-896) antibodyCHD5 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CHD5 (Chromodomain Helicase DNA Binding Protein 5 (CHD5))
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别名
- CHD5
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背景
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Background: Chromatin-remodeling protein that binds DNA through histones and regulates gene transcription. May specifically recognize and bind trimethylated \'Lys-27\' (H3K27me3) and non-methylated \'Lys-4\' of histone H3. Plays a role in the development of the nervous system by activating the expression of genes promoting neuron terminal differentiation. In parallel, it may also positively regulate the trimethylation of histone H3 at \'Lys-27\' thereby specifically repressing genes that promote the differentiation into non-neuronal cell lineages. Tumor suppressor, it regulates the expression of genes involved in cell proliferation and differentiation. Downstream activated genes may include CDKN2A that positively regulates the p53/TP53 pathway, which in turn, prevents cell proliferation. In spermatogenesis, it probably regulates histone hyperacetylation and the replacement of histones by transition proteins in chromatin, a crucial step in the condensation of spermatid chromatin and the production of functional spermatozoa.
Aliases: ATP-dependent helicase CHD5 antibody, CHD 5 antibody, CHD-5 antibody, CHD5 antibody, CHD5_HUMAN antibody, Chromodomain-helicase-DNA-binding protein 5 antibody, DKFZp434N231 antibody, KIAA0444 antibody, RP1-233K16.2 antibody
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UniProt
- Q8TDI0
抗原
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