CBX3 抗体 (AA 10-122)
Quick Overview for CBX3 抗体 (AA 10-122) (ABIN7147701)
抗原
See all CBX3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-122
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Chromobox protein homolog 3 protein (10-122AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CBX3 (Chromobox Homolog 3 (CBX3))
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别名
- CBX3
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背景
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Background: Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at \'Lys-9\', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 \'Lys-9\' trimethylation, mediates the recruitment of the methyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1.
Aliases: CBX 3 antibody, CBX3 antibody, CBX3_HUMAN antibody, Chromobox homolog 3 (HP1 gamma homolog, Drosophila) antibody, Chromobox homolog 3 antibody, Chromobox protein homolog 3 antibody, GAMMA antibody, HECH antibody, Heterochromatin like protein 1 antibody, Heterochromatin protein 1 homolog gamma antibody, Heterochromatin protein HP1 gamma antibody, HP1 gamma antibody, HP1 gamma homolog antibody, HP1Hs gamma antibody, Modifier 2 protein antibody
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UniProt
- Q13185
抗原
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