CHTOP 抗体 (AA 179-248) (Biotin)
Quick Overview for CHTOP 抗体 (AA 179-248) (Biotin) (ABIN7147690)
抗原
See all CHTOP 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 179-248
-
交叉反应
- 人
-
纯化方法
- >95%, Protein G purified
-
免疫原
- Recombinant Human Chromatin target of PRMT1 protein (179-248AA)
-
亚型
- IgG
-
-
anti-Chromatin Target of PRMT1 (CHTOP) (AA 179-248) antibody
CHTOP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chromatin Target of PRMT1 (CHTOP) (C-Term) antibodyCHTOP 适用: 人, 小鼠 WB, IHC, IP, IHC (p), ICC 宿主: 大鼠 Monoclonal KT64 unconjugated
anti-Chromatin Target of PRMT1 (CHTOP) (AA 71-120) antibodyCHTOP 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, Pig, 斑马鱼, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- CHTOP (Chromatin Target of PRMT1 (CHTOP))
-
别名
- CHTOP
-
背景
-
Background: Plays an important role in the ligand-dependent activation of estrogen receptor target genes (PubMed:19858291). May play a role in the silencing of fetal globin genes (PubMed:20688955). Recruits the 5FMC complex to ZNF148, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes (By similarity). Plays an important role in the tumorigenicity of glioblastoma cells. Binds to 5-hydroxymethylcytosine (5hmC) and associates with the methylosome complex containing PRMT1, PRMT5, MEP50 and ERH. The CHTOP-methylosome complex associated with 5hmC is recruited to selective sites on the chromosome, where it methylates H4R3 and activates the transcription of genes involved in glioblastomagenesis (PubMed:25284789).
Aliases: C1orf77 antibody, chromatin target of chromatin target of PRMT1 protein antibody, Chromatin target of PRMT1 antibody, Chromatin target of PRMT1 protein antibody, Chromosome 1 open reading frame 77 antibody, CHTOP antibody, CHTOP_HUMAN antibody, DKFZp547E1010 antibody, FL- RP1-178F15.2 antibody, FL-SRAG antibody, FOP antibody, Friend of PRMT1 antibody, Friend of PRMT1 protein antibody, HT031 antibody, MGC131924 antibody, MGC86949 antibody, OTTHUMP00000035122 antibody, OTTHUMP00000035123 antibody, Pp7704 antibody, RP1 178F15.2 antibody, Small arginine- and glycine-rich protein antibody, Small protein rich in arginine and glycine antibody, SRAG antibody, SRAG-3 antibody, SRAG-5 antibody
-
UniProt
- Q9Y3Y2
抗原
-
