CMKLR1 抗体 (AA 321-373) (Biotin)
Quick Overview for CMKLR1 抗体 (AA 321-373) (Biotin) (ABIN7147550)
抗原
See all CMKLR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 321-373
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Chemokine-like receptor 1 protein (321-373AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
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别名
- CMKLR1
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背景
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Background: Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).
Aliases: CHEMERINR antibody, Chemokine like receptor 1 antibody, Chemokine-like receptor 1 antibody, CHEMR23 antibody, CMKLR1 antibody, CML1_HUMAN antibody, DEZ antibody, G protein coupled receptor ChemR23 antibody, G protein coupled receptor DEZ antibody, G-protein coupled receptor ChemR23 antibody, G-protein coupled receptor DEZ antibody, Orphan G protein coupled receptor antibody, Orphan G protein coupled receptor Dez antibody, Resolvin E1 receptor antibody, RVER1 antibody
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UniProt
- Q99788
抗原
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