CHMP1B 抗体 (AA 1-199)
Quick Overview for CHMP1B 抗体 (AA 1-199) (ABIN7147518)
抗原
See all CHMP1B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-199
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Charged multivesicular body protein 1b protein (1-199AA)
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亚型
- IgG
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anti-Charged Multivesicular Body Protein 1B (CHMP1B) (AA 1-199) antibody
CHMP1B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 1B (CHMP1B) antibodyCHMP1B 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 1B (CHMP1B) (AA 145-199) antibodyCHMP1B 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 1B (CHMP1B) (AA 35-84) antibodyCHMP1B 适用: 人, 小鼠, 大鼠, Cow, 马, 斑马鱼, Bat, 小鸡, Drosophila melanogaster, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 1B (CHMP1B) (N-Term) antibodyCHMP1B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))
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别名
- CHMP1B
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背景
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Background: Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in cytokinesis. Involved in recruiting VPS4A and/or VPS4B and SPAST to the midbody of dividing cells. Involved in HIV-1 p6- and p9-dependent virus release.
Aliases: CHMP1B antibody, C18orf2Charged multivesicular body protein 1b antibody, CHMP1.5 antibody, Chromatin-modifying protein 1b antibody, CHMP1b antibody, Vacuolar protein sorting-associated protein 46-2 antibody, Vps46-2 antibody, hVps46-2 antibody
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UniProt
- Q7LBR1
抗原
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