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CIDEC 抗体 (AA 1-238)

This anti-CIDEC antibody is a 兔 多克隆 antibody detecting CIDEC in ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7147272
发货至: 中国

Quick Overview for CIDEC 抗体 (AA 1-238) (ABIN7147272)

抗原

See all CIDEC 抗体
CIDEC (Cell Death-Inducing DFFA-Like Effector C (CIDEC))

适用

  • 44
  • 23
  • 18

宿主

  • 40
  • 5
  • 1

克隆类型

  • 43
  • 3
多克隆

标记

  • 21
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This CIDEC antibody is un-conjugated

应用范围

  • 38
  • 15
  • 13
  • 13
  • 9
  • 8
  • 5
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-238

    交叉反应

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Cell death activator CIDE-3 protein (1-238AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    CIDEC (Cell Death-Inducing DFFA-Like Effector C (CIDEC))

    别名

    CIDEC

    背景

    Background: Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair. Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1. May act as a CEBPB coactivator in the white adipose tissue to control the expression of a subset of CEBPB downstream target genes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH. When overexpressed in preadipocytes, induces apoptosis or increases cell susceptibility to apoptosis induced by serum deprivation or TGFB treatment. As mature adipocytes, that express high CIDEC levels, are quite resistant to apoptotic stimuli, the physiological significance of its role in apoptosis is unclear. May play a role in the modulation of the response to osmotic stress by preventing NFAT5 to translocate into the nucleus and activate its target genes expression.

    Aliases: Cell death activator antibody, Cell death activator CIDE-3 antibody, Cell death inducing DFFA like effector C antibody, Cell death inducing DFFA like effector protein C antibody, Cell death-inducing DFFA-like effector protein C antibody, CIDE 3 antibody, CIDE C antibody, CIDE3 antibody, CIDEC antibody, CIDEC_HUMAN antibody, Fat specific protein 27 antibody, Fat-specific protein FSP27 homolog antibody, FLJ20871 antibody, FPLD5 antibody, FSP27 antibody

    UniProt

    Q96AQ7
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