CADM1 抗体 (AA 45-344)
Quick Overview for CADM1 抗体 (AA 45-344) (ABIN7147246)
抗原
See all CADM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 45-344
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Cell adhesion molecule 1 protein (45-344AA)
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亚型
- IgG
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anti-Cell Adhesion Molecule 1 (CADM1) (AA 151-250) antibody
CADM1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (AA 365-442) antibodyCADM1 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (Internal Region) antibodyCADM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (AA 65-160) antibodyCADM1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (C-Term) antibodyCADM1 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (AA 45-344) antibodyCADM1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (C-Term) antibodyCADM1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (AA 27-292) antibodyCADM1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (AA 66-94), (N-Term) antibodyCADM1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB22685 unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (AA 69-98), (N-Term) antibodyCADM1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CADM1 (Cell Adhesion Molecule 1 (CADM1))
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别名
- CADM1
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背景
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Background: Mediates homophilic cell-cell adhesion in a Ca2+-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca2+-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. Acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly (By similarity). May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.
Aliases: BL2 antibody, Cadm1 antibody, CADM1_HUMAN antibody, Cell adhesion molecule 1 antibody, DKFZp686F1789 antibody, IgSF4 antibody, IGSF4A antibody, Immunoglobulin superfamily member 4 antibody, MGC149785 antibody, MGC51880 antibody, NECL-2 antibody, NECL2 antibody, Nectin like 2 antibody, Nectin-like protein 2 antibody, RA175 antibody, SgIGSF antibody, Spermatogenic immunoglobulin superfamily antibody, ST17 antibody, sTSLC 1 antibody, Synaptic cell adhesion molecule antibody, SynCAM antibody, SynCAM1 antibody, TSLC-1 antibody, TSLC1 antibody, Tumor suppressor in lung cancer 1 antibody
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UniProt
- Q9BY67
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Activated T Cell Proliferation
抗原
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