CNOT8 抗体 (AA 1-292)
Quick Overview for CNOT8 抗体 (AA 1-292) (ABIN7147105)
抗原
See all CNOT8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-292
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human CCR4-NOT transcription complex subunit 8 protein (1-292AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CNOT8 (CCR4-NOT Transcription Complex, Subunit 8 (CNOT8))
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别名
- CNOT8
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背景
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Background: Has 3\\\'-5\\\' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.
Aliases: CAF 1 antibody, CAF 2 antibody, CAF1 antibody, CAF1 like protein antibody, CAF1-like protein antibody, CAF2 antibody, CALIF antibody, CALIFp antibody, CCR4 associated factor 8 antibody, CCR4 NOT transcription complex subunit 8 antibody, CCR4-associated factor 8 antibody, CCR4-NOT transcription complex subunit 8 antibody, CNOT 8 antibody, Cnot8 antibody, CNOT8_HUMAN antibody, hCAF1 antibody, PGK promoter directed over production antibody, POP 2 antibody, POP2 antibody
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UniProt
- Q9UFF9
抗原
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