CNOT2 抗体 (AA 1-335)
Quick Overview for CNOT2 抗体 (AA 1-335) (ABIN7147097)
抗原
See all CNOT2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-335
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human CCR4-NOT transcription complex subunit 2 protein (1-335AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:500-1:2000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CNOT2 (CCR4-NOT Transcription Complex, Subunit 2 (CNOT2))
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别名
- CNOT2
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背景
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Background: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation, the repressive function may specificly involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of emryonic stem (ES) cell identity.
Aliases: CCR4 associated factor 2 antibody, CCR4 NOT transcription complex subunit 2 antibody, CCR4-associated factor 2 antibody, CCR4-NOT transcription complex subunit 2 antibody, CDC36 antibody, CNOT2 antibody, CNOT2_HUMAN antibody, HSPC131 antibody, MSTP046 antibody, Negative regulator of transcription 2 antibody, NOT2 (negative regulator of transcription 2 yeast) homolog antibody, NOT2 antibody, NOT2H antibody
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UniProt
- Q9NZN8
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance
抗原
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